The Wyoming Valley Conference Division 2 boys basketball schedule includes 12 games for each of the 7 teams – Hanover Area, Holy Redeemer, Lake-Lehman, MMI Prep, Nanticoke, Wyoming Area and Wyoming Seminary.
Each division team plays home-and-home against all of its division rivals.
| Date | Away | Home |
| Dec. 22 | Wyoming Seminary | Nanticoke |
| Dec. 22 | MMI Prep | Wyoming Area |
| Dec. 22 | Holy Redeemer | Hanover Area |
| Jan. 4 | Lake-Lehman | Holy Redeemer |
| Jan. 4 | Nanticoke | MMI Prep |
| Jan. 4 | Hanover Area | Wyoming Seminary |
| Jan. 6 | MMI Prep | Holy Redeemer |
| Jan. 6 | Wyoming Area | Lake-Lehman |
| Jan. 6 | Nanticoke | Hanover Area |
| Jan. 10 | Lake-Lehman | Nanticoke |
| Jan. 10 | Holy Redeemer | Wyoming Area |
| Jan. 10 | Wyoming Seminary | MMI Prep |
| Jan. 13 | MMI Prep | Hanover Area |
| Jan. 13 | Wyoming Area | Nanticoke |
| Jan. 13 | Wyoming Seminary | Lake-Lehman |
| Jan. 17 | Holy Redeemer | Wyoming Seminary |
| Jan. 17 | Hanover Area | Wyoming Area |
| Jan. 17 | Lake-Lehman | MMI Prep |
| Jan. 19 | Wyoming Arwa | Wyoming Seminary |
| Jan. 19 | Nanticoke | Holy Redeemer |
| Jan. 19 | Hanover Area | Lake-Lehman |
| Jan. 21 | Nanticoke | Wyoming Seminary |
| Jan. 21 | Wyoming Area | MMI Prep |
| Jan. 21 | Hanover Area | Holy Redeemer |
| Jan. 24 | Holy Redeemer | Lake-Lehman |
| Jan. 24 | MMI Prep | Nanticoke |
| Jan. 24 | Wyoming Seminary | At Hanover Area |
| Jan. 27 | Holy Redeemer | MMI Prep |
| Jan. 27 | Lake-Lehman | Wyoming Area |
| Jan. 27 | Hanover Area | Nanticoke |
| Jan. 31 | Nanticoke | Lake-Lehman |
| Jan. 31 | Wyoming Area | Holy Redeemer |
| Jan. 31 | MMI Prep | Wyoming Seminary |
| Feb. 3 | Hanover Area | MMI Prep |
| Feb. 3 | Nanticoke | Wyoming Area |
| Feb. 3 | Lake-Lehman | Wyoming Seminary |
| Feb. 7 | Wyoming Seminary | Holy Redeemer |
| Feb. 7 | Wyoming Area | Hanover Area |
| Feb. 7 | MMI Prep | Lake-Lehman |
| Feb. 9 | Wyoming Seminary | Wyoming Area |
| Feb. 9 | Holy Redeemer | Nanticoke |
| Feb. 9 | Lake-Lehman | Hanover Area |
